Article

A Machine-learning-based Method to Detect Degradation of Motor Control Stability with Applications to Diagnosis of Presymptomatic Parkinson’s Disease

2022-10-20

Abstract excerpt

Parkinson’s disease (PD), a neuro-degenerative disorder, is often detected by onset of its motor symptoms such as rest tremor. Unfortunately, motor symptoms appear only when approximately 40%-60% of the dopaminergic neurons in the substantia nigra are lost. In most cases, by the time PD is clinically diagnosed, the disease may already have started 4 to 6 years beforehand. So there is a need for developing a test f...

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Literature Corpus work: 27f1762e-743a-5f6a-a85c-9062472857a2
DOI: 10.1101/2022.10.17.512460

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