Preclinical models to identify molecular drivers of metastasis in paediatric musculoskeletal cancer

Abstract excerpt

Paediatric primary musculoskeletal (MS) cancers such as Ewing’s sarcoma and osteosarcoma account for 5% of childhood malignancies in the UK. Despite advances in surgical intervention and chemotherapy, the survival of patients with these malignancies has not improved substantially over the last 20 years. Current knowledge of the genetic drivers controlling the progression of MS cancers is very limited. Osteosarcoma...

Topics

Open a Topic to create a Post that cites this publication.

• Genomics
• High-Throughput Nucleotide Sequencing
• Inheritance Patterns
• Models, Biological
• Mutation
• Osteosarcoma
• Veterinary Oncology Research
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

27f03c80-e3c4-52b2-b0db-b43222168713

DOI

10.17863/cam.60361