Article

The population frequency of predicted pathogenic variants in commonly-affected genes in CAKUT in the general population

2025-12-17

Abstract excerpt

<title>Abstract</title> <p> Background Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) is the leading cause of kidney failure in children, and renal imaging suggests that it affects one in 200 of the population, one in five of whom are thought to have a genetic cause. This study determined the population frequency of predicted pathogenic variants from the six most commonly-affected CAKUT genes. Met...

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Literature Corpus work: 26e87d7f-f1b4-5dfc-99b4-63d94d2fdfa4
DOI: 10.21203/rs.3.rs-8297749/v1

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