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Contrast-Induced Class Overlap as a Fairness Bottleneck in Dermatological AI: Evidence from HAM10000

2026-06-25

Abstract excerpt

<title>Abstract</title> <p>AI-assisted skin-cancer triage systems, when calibrated for sensitivity, systematically over-predict on darker skin: at a fixed operating point we measure a specificity deficit of -11.0 pp on darker-skin patients (0.715 vs. 0.826 on a high-confidence skin-tone subset, permutation p < 0.0002, Cohen's h = 0.27), translating to an estimated ~89 excess unnecessary referrals per 1,000 darker...

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Literature Corpus work
248306c4-dc1f-5186-9947-903b3571b18e
DOI
10.21203/rs.3.rs-10132969/v1
Open publication

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Contrast-Induced Class Overlap as a Fairness Bottleneck in Dermatological AI: Evidence from HAM10000DOI 10.21203/rs.3.rs-10132969/v1
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