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L-shape distribution of the relative substitution rate (c/μ) observed for SARS-COV-2’s genome, inconsistent with the selectionist theory, the neutral theory and the nearly neutral theory but a near-neutral balanced selection theory: implication on “neutralist-selectionist” debate

2023-01-03

Abstract excerpt

The genomic substitution rate (GSR) of SARS-CoV-2 exhibits a molecular clock feature and does not change under fluctuating environmental factors such as the infected human population (10 0 -10 7 ), vaccination etc.. The molecular clock feature is believed to be inconsistent with the selectionist theory (ST). The GSR shows lack of dependence on the effective population size, suggesting Ohta’s nearly neutral theor...

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Literature Corpus work
22c4822c-dcad-583e-baeb-fb621e31033a
DOI
10.1101/2023.01.01.522435
Open publication

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L-shape distribution of the relative substitution rate (c/μ) observed for SARS-COV-2’s genome, inconsistent with the selectionist theory, the neutral theory and the nearly neutral theory but a near-neutral balanced selection theory: implication on “neutralist-selectionist” debateDOI 10.1101/2023.01.01.522435
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