Article
Genomic, transcriptomic, and metabolomic analysis of Traditional Chinese Medicine plant <i>Oldenlandia corymbosa</i> reveals the biosynthesis and mode of action of anti-cancer metabolites
2022-06-15
Abstract excerpt
Natural products from traditional medicinal plants are valuable candidates for clinical cancer therapy. Plants from the Oldenlandia-Hedyotis complex are popular ingredients of Traditional Chinese Medicine (TCM), however a major hurdle in the plant bioprospecting process of TCM plants is that the active metabolites, their biosynthetic pathways, and mode of action are often unknown. We show that Oldenlandia corymbo...
Topics
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- Bioactive Compounds and Antitumor Agents
- Biological and pharmacological studies of plants
- Cancer-related molecular mechanisms research
- Cancer-related Molecular Pathways
- Microbial Natural Products and Biosynthesis
- Phytochemical compounds biological activities
- Plant biochemistry and biosynthesis
- RNA modifications and cancer
Identifiers and source
- Literature Corpus work
- 22af4968-5c44-5344-a242-03dc9c7fa62f
- DOI
- 10.1101/2022.06.14.496066
