Article

Bulk and single-cell transcriptomics reveal elevated endogenous retrovirus expression linked to immunopathology in severe COVID-19

2026-07-09

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection triggers expression of endogenous retroviruses (ERVs), but whether this persists during coronavirus disease 2019 (COVID-19) and contributes to disease severity has not been well characterized. In this study, we used bulk and single-cell RNA-sequencing data from the blood of severe COVID-19 patients to investigate the role of ERVs in the immunop...

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Literature Corpus work: 21979f71-5766-5c47-af05-1e698119110e
DOI: 10.64898/2026.07.08.737320

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