Article

Modeling the impact of data sharing on variant classification

2021-06-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Many genetic variants are classified, but many more are designated as variants of uncertain significance (VUS). Patient data may provide sufficient evidence to classify VUS. Understanding how long it would take to accumulate sufficient patient data to classify VUS can inform many important decisions such as data sharing, disease management, and functional assay development. <...

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Literature Corpus work: 1fe1118f-5091-5f74-919e-6a7970d24fa2
DOI: 10.1101/2021.06.21.449318

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