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A simplified synthetic route for the photo-sensitizer TPCS 2a - validation against human (T24) and rat (AY27) bladder cancer cell models

2026-08-31

Abstract excerpt

<title>Abstract</title> <p> The tetraphenyl chlorin disulfonate, TPCS <sub>2a</sub> , is a synthetic and light-activated photosensitizer (PS) that is used for photodynamic therapy (PDT) or by releasing entrapped cytotoxic drugs from cancer cell endosomes and lysosomes through the generation of reactive oxygen species (ROS). In this study a new and simplified synthetic route for TPCS <sub>2a</sub> and its pre...

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Literature Corpus work
1d0e56e1-31e2-5eee-ab6a-cd9072083b7b
DOI
10.21203/rs.3.rs-10728553/v1
Open publication

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A simplified synthetic route for the photo-sensitizer TPCS 2a - validation against human (T24) and rat (AY27) bladder cancer cell modelsDOI 10.21203/rs.3.rs-10728553/v1
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