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A DNA foundation model predicts osteoporosis risk genes without proximity bias

2026-03-12

Abstract excerpt

Targets supported by human genetic associations are more than twice as likely to progress from clinical development to approval. Genome-wide association studies are the largest source of genetic evidence for disease risk but linking non-coding variants to effector genes remains a significant barrier to identifying causal targets. Current gene-mapping approaches suffer from proximity bias, largely ignoring distal g...

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Literature Corpus work
1a791a7f-2d02-5695-83ae-b02e6b842672
DOI
10.64898/2026.03.09.707383
Open publication

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A DNA foundation model predicts osteoporosis risk genes without proximity biasDOI 10.64898/2026.03.09.707383
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