Article

Hippocampus responds to mismatches with predictions based on episodic memories but not generalised knowledge

2025-02-05

Abstract excerpt

Prediction errors drive learning by signalling a mismatch between our expectations and reality. The hippocampus plays a key role in mismatch detection, but it is not known what information the hippocampus uses to form expectations. Here we show that the human hippocampus bases its expectations on episodic memories and not generalised schematic knowledge. Across three fMRI experiments, we demonstrate that the hippo...

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Literature Corpus work: 17ff757d-8ac5-5717-bc91-0be4add2b07f
DOI: 10.1101/2025.02.04.636427

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