Article

Paragraph: A graph-based structural variant genotyper for short-read sequence data

2019-05-10

Abstract excerpt

Accurate detection and genotyping of structural variations (SVs) from short-read data is a long-standing area of development in genomics research and clinical sequencing pipelines. We introduce Paragraph, an accurate genotyper that models SVs using sequence graphs and SV annotations. We demonstrate the accuracy of Paragraph on whole-genome sequence data from three samples using long read SV calls as the truth set,...

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Literature Corpus work: 17c999b6-d0ed-54e8-bbdd-2e1f266900cc
DOI: 10.1101/635011

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