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Article

A Clinically Grounded Rule-Based Phenotyping Framework for Identifying Immune-Related Adverse Events in Structured Electronic Health Record Data: A Retrospective EHR Study

2026-07-31

Abstract excerpt

<title>Abstract</title> <p>Background Accurate identification of immune-related adverse events (irAEs) in structured electronic health record (EHR) data remains a major challenge due to the lack of specific diagnostic codes and inconsistent documentation. We propose a clinically grounded, generalizable framework for phenotyping irAEs in structured data, using immune-mediated diarrhea and colitis (IMDC) as a repr...

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Literature Corpus work
173e9964-192c-5d0d-96a1-a7a89f534afc
DOI
10.21203/rs.3.rs-10233239/v1
Open publication

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A Clinically Grounded Rule-Based Phenotyping Framework for Identifying Immune-Related Adverse Events in Structured Electronic Health Record Data: A Retrospective EHR StudyDOI 10.21203/rs.3.rs-10233239/v1
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