Article

Evaluation of a structure-based method for <i>ab initio</i> gene detection using deep learning

2025-12-22

Abstract excerpt

In this work, a novel method for the detection of exons within genomic DNA sequences was implemented and evaluated. This is a structure-based approach, inspired by recent work from Sharma et al., by which nucleotide sequences are converted into physicochemical profiles based on trinucleotide and tetranucleotide mappings that were estimated via molecular dynamics simulations [8,12]. Three deep learning models with...

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Identifiers and source

Literature Corpus work: 1727aebe-6278-52c7-826d-d6142f264716
DOI: 10.64898/2025.12.19.694709

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