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Inactivated Whole Virion Vaccine Protects K18-hACE2 Tg Mice Against Omicron SARS-CoV-2 Variant Via Cross-Reactive T Cells and Non-Neutralizing Antibody Responses

2023-05-01

Abstract excerpt

COVID-19 is a systemic inflammatory disease initiated by SARS-CoV-2 virus infection. Multiple vaccines against Wuhan variant of SARS-CoV-2 have been developed including a whole virion beta-propiolactone-inactivated vaccine based on B.1.1 strain (CoviVac). Since most of the population has been vaccinated by targeting the original or early variants of SARS-CoV-2, the emergence of novel mutant variants raises a conce...

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Literature Corpus work
16e772f2-c5af-5e24-81e8-202776736ee3
DOI
10.2139/ssrn.4430397
Open publication

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Inactivated Whole Virion Vaccine Protects K18-hACE2 Tg Mice Against Omicron SARS-CoV-2 Variant Via Cross-Reactive T Cells and Non-Neutralizing Antibody ResponsesDOI 10.2139/ssrn.4430397
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