Article

Drug Design and Repurposing with DockThor-VS Web Server: Virtual Screening focusing on SARS-CoV-2 Therapeutic Targets and their Non-Synonym Variants

2020-10-23

Abstract excerpt

<title>Abstract</title> <p>The COVID-19 caused by the SARS-CoV-2 virus was declared as a pandemic disease in March 2020 by the World Health Organization (WHO). Structure-Based Drug Design strategies based on docking methodologies have been widely used for both new drug development and drug repurposing to find effective treatments against this disease. In this work, we present the developments implemented in the D...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 15abe32b-ad1b-5a7d-984c-cfb3db67be6f
DOI: 10.21203/rs.3.rs-96789/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Drug Design and Repurposing with DockThor-VS Web Server: Virtual Screening focusing on SARS-CoV-2 Therapeutic Targets and their Non-Synonym VariantsDOI 10.21203/rs.3.rs-96789/v1Read

Virtual screening FDA approved drugs against multiple targets of SARS‐CoV‐2Semantic proximity Read

Repurposing drugs for treatment of SARS-CoV-2 infection: Computational design insights into mechanisms of actionSemantic proximity Read

In Silico Drug Discovery: The Next Frontier in the Fight Against SARS-CoV-2Semantic proximity Read

A Multi-Pronged Approach Targeting SARS-CoV-2 Proteins Using Ultra-Large Virtual ScreeningSemantic proximity Read

Study of combining virtual screening and antiviral treatments of the Sars-CoV-2 (Covid-19)Semantic proximity Read

A Structure-Based Computational Pipeline for Broad-Spectrum Antiviral DiscoverySemantic proximity Read

Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2Semantic proximity Read

A Comprehensive Review of Drug Repurposing Strategies against Known Drug Targets of COVID-19Semantic proximity Read

Drug repurposing for SARS-CoV-2: a high-throughput molecular docking, molecular dynamics, machine learning, and DFT studySemantic proximity Read

A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screeningSemantic proximity Read

Integrated Docking and Enhanced Sampling Based Selection of Repurposing Drugs for SARS-CoV-2 by Targeting Host Dependent FactorsSemantic proximity Read

Virtual Screening Based Prediction of Potential Drugs for COVID-19Semantic proximity Read