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Probiotic-derived strain-specific metabolites ameliorate metabolic dysfunction-associated steatotic liver disease through modulation of the gut-liver axis

2025-07-15

Abstract excerpt

<title>Abstract</title> <p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent chronic liver condition lacking approved treatments, where the gut-liver axis is a key therapeutic target. This study aimed to identify novel probiotic strains and elucidate their strain-specific mechanisms by profiling their functional metabolites. We first investigated gut microbiota alterations in a human...

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Literature Corpus work
1531a16d-9afd-5c7b-82c2-617664fcb865
DOI
10.21203/rs.3.rs-7073349/v1
Open publication

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Probiotic-derived strain-specific metabolites ameliorate metabolic dysfunction-associated steatotic liver disease through modulation of the gut-liver axisDOI 10.21203/rs.3.rs-7073349/v1
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