Article

Clinical Validation of a Non-Invasive Prenatal Test for Genome-Wide Detection of Fetal Copy Number Variants

2015-12-02

Abstract excerpt

1. <h4>ABSTRACT</h4> <h4>Background</h4> Current cell-free DNA (cfDNA) assessment of fetal chromosomes does not analyze and report on all chromosomes. Hence, a significant proportion of fetal chromosomal abnormalities are not detectable by current non-invasive methods. Here we report the clinical validation of a novel NIPT designed to detect genome-wide gains and losses of chromosomal material ≥7 Mb and losses a...

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Literature Corpus work: 13b4f2ec-4778-5c17-ac14-2a4e5a816b61
DOI: 10.1101/033555

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