Article

Mechanism of circDYM/CEBPB/ZC3H4 axis in LPS-induced Microglial Apoptosis

2023-06-28

Abstract excerpt

Circular RNAs (circRNAs) are a subtype of non-coding RNAs and contribute to the various central nervous system (CNS) diseases. However, microglia apoptosis which is regulated by circRNAs in major depressive disorder (MDD) is incompletely clear. Herein, we have shown that the circular RNA DYM (circDYM) binds to the transcription factor CEBPB, thereby releasing repression of CEBPB target gene ZC3H4 transcription. Th...

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Literature Corpus work: 12b55094-2561-584c-b010-b07f0a28a7b2
DOI: 10.21203/rs.3.rs-3094444/v1

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