Network pharmacology and molecular docking in the exploration of Taohong Siwu decoction against coronary heart disease

Abstract excerpt

Taohong Siwu decoction (TSD) is a traditional Chinese medicine formulation that has been widely used to treat coronary heart disease (CHD), although its underlying biological mechanism is unknown. Using gene or pathway terminology for analytical studies, protein‒protein interaction (PPI) network-based analysis, and PPI cluster recognition, we performed network pharmacology and molecular docking methods in this res...

Topics

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• Atherosclerosis and Cardiovascular Diseases
• Cardiac Fibrosis and Remodeling
• Cardiovascular Function and Risk Factors
• Lipid metabolism and disorders
• NF-κB Signaling Pathways
• Traditional Chinese Medicine Analysis
• Traditional Chinese Medicine Studies

Identifiers and source

Literature Corpus work

1284e376-7ee4-574c-8db9-2e55c93bccd3

DOI

10.21203/rs.3.rs-3263534/v1