Back to search

Article

Single-cell and transcriptome identification of biomarkers and regulatory mechanisms associated with macrophage-related cell death in diabetic nephropathy

2026-06-22

Abstract excerpt

<title>Abstract</title> <p>Diabetic nephropathy (DN) is a leading cause of end-stage renal disease, yet the role of macrophage-related cell death (MGCD) in its pathogenesis remains poorly understood. To address this, we integrated bulk transcriptomic data from three public datasets (GSE96804, GSE142153, GSE30528) and single-cell RNA sequencing data (GSE131882) with 73 MGCD-related genes to identify potential biom...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1221fe82-f3c2-500d-bd52-d92ed69cfb4a
DOI
10.21203/rs.3.rs-9792813/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Single-cell and transcriptome identification of biomarkers and regulatory mechanisms associated with macrophage-related cell death in diabetic nephropathyDOI 10.21203/rs.3.rs-9792813/v1
Single-cell and transcriptome analysis reveals TAL cells in diabetic nephropathySemantic proximity
ALOX5, a novel diagnostic and prognostic marker associated with immune cells and ferroptosis in diabetic kidney diseaseSemantic proximity
Single-Cell RNA Sequencing Profiles Identify Important Pathophysiologic Factors in the Progression of Diabetic NephropathySemantic proximity
Uncovering key markers and therapeutic targets for renal fibrosis in diabetic kidney disease through bulk and single-cell RNA sequencingSemantic proximity
Identification of a novel immune landscape signature as effective diagnostic markers related to immune cell infiltration in diabetic nephropathySemantic proximity
Single-cell transcriptomes reveal a molecular link between diabetic kidney and retinal lesionsSemantic proximity
Bioinformatics Identification and Validation of Pyroptosis-Related Diagnostic Biomarkers in Diabetic NephropathySemantic proximity
Identification of necroptosis-related features in diabetic nephropathy and analysis of their immune microenvironent and inflammatory responseSemantic proximity
Identification and validation of disulfidptosis-related gene signatures and their subtype in diabetic nephropathySemantic proximity
Single-cell RNA and transcriptome sequencing profiles identify immune-associated key genes in the development of diabetic kidney diseaseSemantic proximity
Single-Cell Transcriptional Landscape Reveals the Regulatory Network and Its Heterogeneity of Renal Mitochondrial Damages in Diabetic Kidney DiseaseSemantic proximity
Identification of Biomarkers Associated with Diagnosis of Diabetic Nephropathy Patients Based on Bioinformatics and Machine LearningSemantic proximity
Select a neighboring publication to make it the new centre.