Back to search

Article

Beyond Seizure Burden: Seizure Semiology, but not Frequency, is Associated with Caregiver-Reported Autistic Behaviors in SYNGAP1-DEE

2026-04-21

Abstract excerpt

1. <h4>Purpose</h4> SYNGAP1-related developmental and epileptic encephalopathy (SYNGAP1-DEE) is characterized by high rates of both epilepsy and autism spectrum disorder (ASD). While the clinical spectrum is well-documented, the link between specific seizure semiologies and caregiver-reported autistic behaviors is not well understood. This study analyzed the correlation between ten distinct seizure types, their f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
111de74b-0d97-566c-a864-e7087a768a78
DOI
10.64898/2026.04.19.26351217
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Beyond Seizure Burden: Seizure Semiology, but not Frequency, is Associated with Caregiver-Reported Autistic Behaviors in SYNGAP1-DEEDOI 10.64898/2026.04.19.26351217
Clinical signatures of SYNGAP1-related disorders through data integration.Semantic proximity
Clinical signatures of<i>SYNGAP1-</i>related disorders through data integrationSemantic proximity
Phenotypic characterization of individuals with SYNGAP1 pathogenic variants reveals a potential correlation between posterior dominant rhythm and developmental progressionSemantic proximity
Adult Phenotype of SYNGAP1 -DEESemantic proximity
Clinical Analysis of SYNGAP1 Variant-Related Neurodevelopmental Disorders in Chinese Children.Semantic proximity
Understanding Seizures in Malan Syndrome Through Caregiver Reports: A Cross-Sectional StudySemantic proximity
Comprehensive phenotypes of patients with SYNGAP1-related disorder reveals high rates of epilepsy and autism.Semantic proximity
Clinical and Genetic Profile of Autism Spectrum Disorder-Epilepsy (ASD-E) Phenotype: Two Sides of the Same Coin!Semantic proximity
Behavioral phenotypes of childhood idiopathic epilepsies.Semantic proximity
SYNGAP1-related disorder: pathophysiology, epilepsy, cognitive and behavioral phenotypes, and precision therapeutic approaches.Semantic proximity
Autism Spectrum Disorder and Epilepsy.Semantic proximity
Clinical Characteristics and Treatment Experience of Individuals with SCN8A Developmental and Epileptic Encephalopathy (SCN8A-DEE): Findings from an Online Caregiver SurveySemantic proximity
Select a neighboring publication to make it the new centre.