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Article

Tick-borne coinfections modulate CD8+ T cell response and progressive leishmaniosis

2025-04-07

Abstract excerpt

<h4>ABSTRACT</h4> Leishmania infantum causes human Visceral Leishmaniasis and Leishmaniosis (CanL) in reservoir host, dogs. As infection progresses to disease in both humans and dogs there is a shift from controlling, Type 1, immunity to a regulatory, exhausted, T cell phenotype. In endemic areas, association between tickborne coinfections (TBC) and Leishmania diagnosis and/or clinical severity has been demonstr...

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Literature Corpus work
0ee227c7-623d-50bd-8280-385c5f13b995
DOI
10.1101/2025.04.03.647089
Open publication

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Tick-borne coinfections modulate CD8+ T cell response and progressive leishmaniosisDOI 10.1101/2025.04.03.647089
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