Article

Manu on Lenti G2B Gene Therapy for β-Thalassemia

2024-04-24

Abstract excerpt

<title>Abstract</title> <p>Gene therapy, particularly lentiviral vector-based approaches, has emerged as a crucial alternative for treating β-thalassemia, one of the most prevalent monogenic disorders worldwide. This study focuses on overcoming clinical challenges associated with existing HBB lentiviral vectors, characterized by suboptimal titers and inadequate β-globin expression. We have advanced the BB305 lent...

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Literature Corpus work: 0dfd9d10-6335-5de9-8637-b959b8eaed56
DOI: 10.21203/rs.3.rs-4249953/v1

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