Article

Analysis of heterozygous <i>PRKN</i> variants and copy number variations in Parkinson’s disease

2020-05-12

Abstract excerpt

<h4>Background</h4> Biallelic PRKN mutation carriers with Parkinson’s disease (PD) typically have an earlier disease onset, slow disease progression and, often, different neuropathology compared to sporadic PD patients. However, the role of heterozygous PRKN variants in the risk of PD is controversial. <h4>Objectives</h4> We aimed to examine the association between heterozygous PRKN variants, including single nucl...

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Literature Corpus work: 0d39c412-2939-5ffd-b689-162d4d3aff82
DOI: 10.1101/2020.05.07.20072728

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