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Different Recurrence and Growth Pattern of Gliomatous Foci after Mesenchymal Stem Cell Harbouring the Herpes Simplex Thymidine Kinase Gene Transplantation in Multifocal Glioblastoma Multiform: A Clinical Case Report

2021-06-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Glioblastoma multiform (GBM) as a malignant brain tumor has poor prognosis despite the current therapies. Suicide gene therapy is one of the most widespread cancer gene therapies which requires mRNA encoding a pro-drug activating enzyme transduced into the vector such as Mesenchymal Stem Cells (MSCs) that injects into the tumor tissue and leads to tumor suppress...

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Literature Corpus work
07ac5da3-785a-5504-940b-9d71a5f1755d
DOI
10.21203/rs.3.rs-556539/v1
Open publication

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