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Estradiol induces global changes in miRNA expression in endometrial cancer cells and upregulates oncogenic miR-182

2024-05-14

Abstract excerpt

<h4>ABSTRACT</h4> Endometrial cancer (EC) occurs mainly in perimenopausal age. Risk factors are associated with unopposed estrogen stimulation of the endometrium. There are two main types of EC, EC1 and EC2. The pathogenesis of EC1 is estrogen-dependent. MiRNAs are small RNAs that regulate gene expression posttranscriptionally. They are induced by estrogens in different hormone-dependent neoplasias including brea...

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Literature Corpus work
079e732e-4476-564f-89f7-b5e19f961467
DOI
10.1101/2024.05.12.593753
Open publication

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Estradiol induces global changes in miRNA expression in endometrial cancer cells and upregulates oncogenic miR-182DOI 10.1101/2024.05.12.593753
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