Back to search

Article

Multimodal Sleep Physiology Reconstructs Cerebrospinal Fluid Dynamics: A Candidate Digital Biomarker from Noninvasive Sensing

2026-07-28

Abstract excerpt

Cerebrospinal fluid (CSF) dynamics are clinically important but can presently be measured only with expensive, non-portable imaging or invasive monitoring, precluding scalable assessment. We investigated whether CSF flow in the cerebral aqueduct can be reconstructed from noninvasive physiology recorded during sleep. In 22 healthy adults, with independent validation in 14 additional adults, regularized linear and e...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
06288c8d-5d68-5a83-8772-f6bf62d816df
DOI
10.64898/2026.07.27.26359039
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Multimodal Sleep Physiology Reconstructs Cerebrospinal Fluid Dynamics: A Candidate Digital Biomarker from Noninvasive SensingDOI 10.64898/2026.07.27.26359039
Infra-slow (<0.1 Hz) modulation of human brain pulsations in awake and sleep statesSemantic proximity
Non-invasive intracranial pressure waveform reconstruction with deep learningSemantic proximity
Wearable Sleep Staging: From Neurophysiology to Clinical Translation—A Comprehensive ReviewSemantic proximity
The sleep EEG envelope: a novel, neuronal firing-based human biomarkerSemantic proximity
A Zero-Burden Sleep Foundation Model Built on Cardiorespiratory Signals from 1,400,000+ Hours of Multi-Ethnic Sleep RecordingsSemantic proximity
A Foundation Model for Sleep-Based Risk Stratification and Clinical OutcomesSemantic proximity
A Novel Three-dimensional Multilayer Electroencephalography ParadigmSemantic proximity
Wearable 16-channel electroencephalography for 8-day continuous monitoringSemantic proximity
Unsupervised Representation Learning Reveals Individualized Neurophysiological ProfilesSemantic proximity
A novel hybrid Wireless Integrated Sensing Detector for simultaneous EEG and MRI (WISDEM)Semantic proximity
A Multimodal Sleep Foundation Model for Disease PredictionSemantic proximity
CardioFM: A Multimodal Foundation Model for Joint ECG and PPG Representation LearningSemantic proximity
Select a neighboring publication to make it the new centre.