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Adamantinomatous Craniopharyngioma Cyst Fluid can Trigger Inflammatory Activation of Microglia to Damage the Hypothalamic Neurons by Inducing the Production of β-Amyloid

2021-12-23

Abstract excerpt

<h4>Introduction: </h4> The mechanism by which adamantinomatous craniopharyngioma (ACP) damages the hypothalamus is still unclear. Cyst fluid rich in lipids and inflammatory factors is a characteristic pathological manifestation of ACP and may play a very important role in hypothalamic injury caused by tumors. <h4>Objective: </h4> To construct a reliable animal model of ACP cyst fluid-induced hypothalamic injury a...

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Literature Corpus work
046b319c-fe43-5482-b2ad-f5ea377dc9e7
DOI
10.21203/rs.3.rs-1186006/v1
Open publication

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Adamantinomatous Craniopharyngioma Cyst Fluid can Trigger Inflammatory Activation of Microglia to Damage the Hypothalamic Neurons by Inducing the Production of β-AmyloidDOI 10.21203/rs.3.rs-1186006/v1
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