Article

Genomic and transcriptomic data analyses highlight <i>KPNB1</i> and <i>MYL4</i> as novel risk genes for congenital heart disease

2022-01-08

Abstract excerpt

Congenital heart defects (CHD) are structural defects of the heart affecting approximately 1% of newborns. CHDs exhibit a complex inheritance pattern. While genetic factors are known to play an important role in the development of CHD, relatively few variants have been discovered so far and very few genome-wide association studies (GWAS) have been conducted. We performed a GWAS of general CHD and five CHD subgroup...

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Literature Corpus work: 042e684e-bf57-52fa-8bcd-1cae6d14f033
DOI: 10.1101/2022.01.07.22268881

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