Article

The engineered ORF56–57 deletion mutant leads to attenuation of an Asian koi herpesvirus strain

2024-01-01

Abstract excerpt

Koi herpesvirus (KHV) poses a significant threat to the koi and common carp aquaculture industry due to its high mortality rate among infected fish. In this study, we successfully isolated an Asian KHV strain designated as SS09 and investigated the potential attenuation of the SS09 through the deletion of open reading frames 56 and 57 (ORF56–57). By utilizing homologous recombination technology, we generated a mut...

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Literature Corpus work: 022cfa4d-cd32-5e1c-9914-fe861877060d
DOI: 10.1016/j.aquaculture.2023.740263

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