Article

Biomedical Large Language Models and Prompt Engineering for Causality Assessment of Individual Case Safety Reports in Pharmacovigilance

2026-02-24

Abstract excerpt

<h4>Background</h4> Biomedical Large Language Models (LLMs) combined with prompt engineering offer domain-specific reasoning, yet their application to individual-level causality assessment remains unexplored. This study evaluated five combinations of biomedical LLMs, prompting strategies, and causality algorithms by comparing their agreement with two human expert evaluators. <h4>Research design and methods</h4>...

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Literature Corpus work: 00ddefc1-8299-55ea-b807-30bf96b4f572
DOI: 10.64898/2026.02.19.26346467

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