Article

AnimalGAN: A Generative Adversarial Network Model Alternative to Animal Studies for Clinical Pathology Assessment

2023-03-27

Abstract excerpt

Animal studies are unavoidable in evaluating chemical and drug safety. Generative Adversarial Networks (GANs) can generate synthetic animal data by learning from the legacy animal study results, thus serving as an alternative approach to assess untested chemicals. AnimalGAN, a GAN method to simulate 38 rat clinical pathology measures, was developed with significant robustness even for the drugs that vary significa...

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Literature Corpus work: 00af0246-033d-52b5-a1fe-4c37d1b99c1d
DOI: 10.1101/2023.03.25.534230

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