Article

Targeting long non-coding RNA MALAT1 reverses cancerous phenotypes of breast cancer cells through microRNA-561-3p/TOP2A axis.

2022-12-15

Abstract excerpt

<title>Abstract</title><p>Non-coding RNAs, including Inc-RNA and miRNA, had been reported to regulate gene expression and were associated with cancer progression. MicroRNA-561-3p (miR-561-3p), as a tumor suppressor, has been reported to play a role in preventing cancer cell progression, and MALAT1 (Lnc-RNA) has also been demonstrated to promote malignancy in various cancer, such as breast cancer (BC). In this stud...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 00620480-1eee-5f8c-9cf4-6b55555a9f22
DOI: 10.21203/rs.3.rs-2344913/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Targeting long non-coding RNA MALAT1 reverses cancerous phenotypes of breast cancer cells through microRNA-561-3p/TOP2A axis.DOI 10.21203/rs.3.rs-2344913/v1Read

LncRNA MALAT1 promotes breast cancer progression and doxorubicin resistance via regulating miR-570–3pSemantic proximity Read

The MALAT1-breast cancer interplay: insights and implicationsSemantic proximity Read

Clinicopathological and prognostic significance of long noncoding RNA MALAT1 in human cancers: a review and meta-analysisSemantic proximity Read

LncRNA FLVCR1-AS1 promotes proliferation, migration and activates Wnt/β-catenin pathway through miR-381-3p/CTNNB1 axis in breast cancerSemantic proximity Read

Sp1-activated Long Noncoding RNA NCK1-AS1 Facilitates Cell Growth of Breast Cancer via Sponging miR-361-5p Semantic proximity Read

Long non-coding RNA MALAT1 regulates ovarian cancer cell proliferation, migration and apoptosis through Wnt/β-catenin signaling pathway.Semantic proximity Read

Long non-coding RNA MALAT1 in hematological malignancies and its clinical applicationsSemantic proximity Read

A novel lncRNA AC112721.1 promotes the progress of triple-negative breast cancer by directly binding to THBS1 and regulating the miR-491-5p/C2CD2L axisSemantic proximity Read

PCMT1 has Potential Prognostic Value and Promotes Cell Growth and Motility in Breast CancerSemantic proximity Read

LncRNA DDX11-AS1 promotes breast cancer progression via targeting the miR-30c-5p/MTDH axisSemantic proximity Read

MicroRNA-561-3p indirectly regulates the PD-L1 expression by targeting ZEB1, HIF1A, and MYC genes in breast cancerSemantic proximity Read

MiR-519e-5p regulates malignant phenotype of breast cancer cells through binding to CTPS1.Semantic proximity Read