Article
Intron 2 and exon 3 sequences may be involved in the susceptibility to develop Takayasu arteritis.
International journal of cardiology - 1 Oct 1998
Rodríguez-Reyna T S, Zúñiga-Ramos J, Salgado N, Hernández-Martínez B, Vargas-Alarcón G, Reyes-López P A, Granados J
Abstract excerpt
We studied Major Histocompatibility Complex (MHC) Class I and Class II genes in seven Mexican Mestizo patients with Takayasu arteritis. Takayasu arteritis is an uncommon condition in Mexican Mestizo, however, previous studies report association of the disease in this population with Human Leukocy...
Topics
- DNA
- Electrophoresis, Agar Gel
- Exons
- Genes, MHC Class I
- Genes, MHC Class II
- Genetic Predisposition to Disease
- Histocompatibility Testing
- Humans
- Introns
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Sequence Analysis, DNA
- Takayasu Arteritis