Article
The clinical relevance of cytokeratin phenotyping in needle biopsy of liver metastasis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Dec 2003
Tot Tibor, Samii Siri
Abstract excerpt
Although cytokeratin (CK) phenotyping of metastatic tumors is now routine in many laboratories, the clinical relevance of the procedure has seldom been addressed. We carried out a prospective clinical study of 134 consecutive cases of metastatic adenocarcinoma of the liver diagnosed by needle biopsies stained routinely for CK20 and CK7. The most probable localization of the primary tumor, deduced from this...
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