Granulosa cell tumor of the ovary. Immunohistochemical evidence of low proliferative activity and virtual absence of mutation of the p53 tumor-suppressor gene.

doi:10.1159/000010077

Article

Granulosa cell tumor of the ovary. Immunohistochemical evidence of low proliferative activity and virtual absence of mutation of the p53 tumor-suppressor gene.

Gynecologic and obstetric investigation - 1 Jan 1999

Horny H P, Marx L, Kröber S, Lüttges J, Kaiserling E, Dietl J

Abstract excerpt

BACKGROUND AND METHODS: Because the use of immunohistochemistry in the diagnosis of granulosa cell tumor (GCT) has not been fully explored, routinely processed (formalin-fixed, paraffin-embedded) tissue from 11 GCT, adult type, was investigated immunohistochemically (ABC method) with a broad spectrum of antibodies against various markers, including p53 and Ki-67. All of the tumors exhibited typical morphology,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Granulosa cell tumor of the ovary. Immunohistochemical evidence of low proliferative activity and virtual absence of mutation of the p53 tumor-suppressor gene.

Abstract excerpt

Topics

Related research