Article
Granulosa cell tumor of the ovary. Immunohistochemical evidence of low proliferative activity and virtual absence of mutation of the p53 tumor-suppressor gene.
Gynecologic and obstetric investigation - 1 Jan 1999
Horny H P, Marx L, Kröber S, Lüttges J, Kaiserling E, Dietl J
Abstract excerpt
BACKGROUND AND METHODS: Because the use of immunohistochemistry in the diagnosis of granulosa cell tumor (GCT) has not been fully explored, routinely processed (formalin-fixed, paraffin-embedded) tissue from 11 GCT, adult type, was investigated immunohistochemically (ABC method) with a broad spec...
Topics
- Actins
- Aged
- Cell Division
- Cell Nucleus
- Female
- Genes, p53
- Granulosa Cell Tumor
- Humans
- Immunohistochemistry
- Inhibins
- Ki-67 Antigen
- Macrophages
- Middle Aged
- Muscle, Smooth
- Mutation
- Ovarian Neoplasms
- Receptors, Progesterone
- T-Lymphocytes