Article
Association between nm23-H1 expression, proliferation and apoptosis in non-small cell lung carcinomas.
Clinical & experimental metastasis - 1 Oct 1998
Volm M, Mattern J, Koomägi R
Abstract excerpt
Twelve non-small cell lung carcinomas and adjacent normal lung tissues were examined for mutations of the nm23-H1 gene by using SSCP analysis and for an expression of the nm23-H1 protein by immunohistochemistry. No mutations could be found in either the carcinomas or in the adjacent normal tissue...
Topics
- Apoptosis
- Biomarkers, Tumor
- Carcinoma, Non-Small-Cell Lung
- Cell Division
- Doxorubicin
- Drug Resistance, Neoplasm
- Female
- Gene Expression
- Genes, myc
- Humans
- Immunochemistry
- Lung Neoplasms
- Lymphatic Metastasis
- Male
- Middle Aged
- Monomeric GTP-Binding Proteins
- Mutation
- NM23 Nucleoside Diphosphate Kinases