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Article

The morphogenesis of granular and lattice corneal dystrophy - A mutation combination hypothesis.

Medical hypotheses - 1 Dec 2020

Sabir Mohammed

Abstract excerpt

Mutations in the BIGH3 gene encoding for keratoepithelin protein have been described in different corneal dystrophies viz. granular corneal dystrophy, lattice corneal dystrophy, and their different clinical subtypes. Even though linked to the BIGH3 gene, the role of BIGH3 gene in the pathogenesis of corneal lattice dystrophy and corneal granular dystrophy remains to be elucidated. We describe the probable...

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Share to Corneal Dystrophies, Hereditary
Share to DNA Mutational Analysis
Share to Extracellular Matrix Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33039949
DOI: 10.1016/j.mehy.2020.110291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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