Article
Low penetrance in the long-QT syndrome: clinical impact.
Circulation - 2 Feb 1999
Priori S G, Napolitano C, Schwartz P J
Abstract excerpt
BACKGROUND: It is still currently held that most patients affected by the long-QT syndrome (LQTS) show QT interval prolongation or clinical symptoms. This is reflected by the assumption in linkage studies of a penetrance of 90%. We had previously suggested that a larger-than-anticipated number of...
Topics
- Adolescent
- Adult
- Child
- Diagnosis, Differential
- Electrocardiography
- Female
- Humans
- Long QT Syndrome
- Male
- Middle Aged
- Mutation
- Pedigree
- Polymorphism, Single-Stranded Conformational