Article
Two roles for the leucine-responsive regulatory protein in expression of the alanine catabolic operon (dadAB) in Klebsiella aerogenes.
Journal of bacteriology - 1 Feb 1999
Janes B K, Bender R A
Abstract excerpt
The lrp gene, which codes for the leucine-responsive regulatory protein (Lrp), was cloned from Klebsiella aerogenes W70. The DNA sequence was determined, and the clone was used to create a disruption of the lrp gene. The lack of functional Lrp led to an increased expression of the alanine catabol...
Topics
- Alanine
- Bacterial Proteins
- Cloning, Molecular
- D-Amino-Acid Oxidase
- DNA-Binding Proteins
- Enzyme Induction
- Gene Expression Regulation, Bacterial
- Gene Expression Regulation, Enzymologic
- Genotype
- Glutamate Synthase
- Kinetics
- Klebsiella pneumoniae
- Leucine-Responsive Regulatory Protein
- Molecular Sequence Data
- Operon
- Transcription Factors