Article
Genetic susceptibility to gluten sensitive enteropathy in Irish setter dogs is not linked to the major histocompatibility complex.
Tissue antigens - 1 Dec 1998
Polvi A, Garden O A, Houlston R S, Maki M, Batt R M, Partanen J
Abstract excerpt
Gluten sensitive enteropathy (GSE) in Irish setter dogs has been proposed as an animal model for human celiac disease (CD), in which the major histocompatibility complex (MHC) class II alleles HLA DQA1*0501 and DQB1*0201 play an important role. To investigate whether an orthologous MHC class II r...
Topics
- Alleles
- Animals
- Celiac Disease
- Disease Models, Animal
- Dogs
- Female
- Genes, MHC Class II
- Genetic Linkage
- Genetic Predisposition to Disease
- Glutens
- Haplotypes
- Male
- Pedigree