Odontogenic myxomas are not associated with activating mutations of the Gs alpha gene.

Article

Odontogenic myxomas are not associated with activating mutations of the Gs alpha gene.

Anticancer research - 1 Jan 2000

Boson W L, Gomez R S, Araujo L, Kalapothakis E, Friedman E, De Marco L

Abstract excerpt

BACKGROUND: Myxoma is a rare bone tumor of the mandible and maxillary sinus whose etiology and underlying molecular mechanisms remain unknown. Mutations that inhibit the GTPase activity of the a subunit of the stimulating G protein (Gsa) have been demonstrated in the myocardium of patients with M...

Topics

Biopsy
DNA, Neoplasm
GTP Phosphohydrolases
GTP-Binding Protein alpha Subunits, Gs
Humans
Jaw Neoplasms
Mutation
Myxoma
Odontogenic Tumors
Polymerase Chain Reaction

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