Parallels between tuberous sclerosis complex and neurofibromatosis 1: common threads in the same tapestry.

doi:10.1016/s1071-9091(98)80006-5

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Article

Parallels between tuberous sclerosis complex and neurofibromatosis 1: common threads in the same tapestry.

Seminars in pediatric neurology - 1 Dec 1998

Gutmann D H

Abstract excerpt

Neurofibromatosis type 1 (NF1) and tuberous sclerosis complex (TSC) represent two neurocutaneous disorders in which affected individuals develop tumors at an increased frequency. Although the clinical manifestations of these disorders are distinctive, the identification of the genes responsible f...

Topics

Calcium-Calmodulin-Dependent Protein Kinases
Cell Division
Child
DNA Mutational Analysis
Diagnosis, Differential
Genes, Tumor Suppressor
Genetic Predisposition to Disease
Humans
Neurofibromatosis 1
Signal Transduction
Tuberous Sclerosis

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