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Article

The mutation rates of di-, tri- and tetranucleotide repeats in Drosophila melanogaster.

Molecular biology and evolution - 1 Dec 1998

Schug M D, Hutter C M, Wetterstrand K A, Gaudette M S, Mackay T F, Aquadro C F

Abstract excerpt

In a recent study, we reported that the combined average mutation rate of 10 di-, 6 tri-, and 8 tetranucleotide repeats in Drosophila melanogaster was 6.3 x 10(-6) mutations per locus per generation, a rate substantially below that of microsatellite repeat units in mammals studied to date (range = 10(-2)-10(-5) per locus per generation). To obtain a more precise estimate of mutation rate for dinucleotide repeat...

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PMID: 9866209
DOI: 10.1093/oxfordjournals.molbev.a025901

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