Article
The mutation rates of di-, tri- and tetranucleotide repeats in Drosophila melanogaster.
Molecular biology and evolution - 1 Dec 1998
Schug M D, Hutter C M, Wetterstrand K A, Gaudette M S, Mackay T F, Aquadro C F
Abstract excerpt
In a recent study, we reported that the combined average mutation rate of 10 di-, 6 tri-, and 8 tetranucleotide repeats in Drosophila melanogaster was 6.3 x 10(-6) mutations per locus per generation, a rate substantially below that of microsatellite repeat units in mammals studied to date (range...
Topics
- Africa
- Alleles
- Animals
- Dinucleotide Repeats
- Drosophila melanogaster
- Evolution, Molecular
- Female
- Gene Library
- Genetic Markers
- Heterozygote
- Microsatellite Repeats
- Models, Genetic
- Mutation
- Polymerase Chain Reaction
- Regression Analysis
- Time
- Trinucleotide Repeats
- United States