Article
The frequency of 844ins68 mutation in the cystathionine beta-synthase gene is not increased in patients with venous thrombosis.
Haematologica - 1 Nov 1998
Franco R, Maffei F, Lourenço D, Piccinato C, Morelli V, Thomazini I, Zago M
Abstract excerpt
BACKGROUND AND OBJECTIVES: A frequent mutation in the cystathionine beta-synthase (CBS) gene (844ins68, a 68-bp insertion in the coding region of exon 8) was recently discovered. In the present study we investigated this mutation as a candidate risk factor for venous thrombosis. DESIGN AND METHODS: The prevalence of the 844ins68 CBS mutation was determined in 101 patients with objectively diagnosed deep venous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.