Sequence diversity of flagellin (fliC) alleles in pathogenic Escherichia coli.

doi:10.1128/JB.181.1.153-160.1999

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Article

Sequence diversity of flagellin (fliC) alleles in pathogenic Escherichia coli.

Journal of bacteriology - 1 Jan 1999

Reid S D, Selander R K, Whittam T S

Abstract excerpt

To study the molecular evolution of flagellin, the protein subunit specifying flagellar (H) antigens, the fliC genes from 15 pathogenic strains of Escherichia coli were amplified by PCR and sequenced. Comparison of fliC sequences of H6 and H7 strains revealed that alleles have a mosaic structure...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Cloning, Molecular
DNA Primers
DNA, Bacterial
Escherichia coli
Escherichia coli O157
Evolution, Molecular
Flagellin
Genes, Bacterial
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Molecular Sequence Data

Mutation

Phylogeny

Polymorphism, Genetic

Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 9864325
DOI: 10.1128/JB.181.1.153-160.1999
PMCID: PMC103544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9864325-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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