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Article

Sperm segregation analysis of a complex chromosome rearrangement, 2;22;11, by whole chromosome painting

1 Jan 1998

Abstract excerpt

Using the human sperm-hamster oocyte fusion technique and whole chromosome painting, we studied sperm chromosome segregation in a male heterozygous for a complex chromosome rearrangement, 46,XY,-2, +der(2)t(2;11)(q13; q23),-11,+der(11)t(11;22)(q23;q11.2),-22, +der(22)t(2;22)(q13; q11.2). A total of 208 sperm complements were analyzed. The frequency of sperm carrying a normal or a balanced complement was 13.5%...

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Share to Chromosomal and Genetic Variations
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Identifiers

PMID: 9858818
DOI: 10.1159/000015101

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