Article
Single nucleotide polymorphism spectra in newborns and centenarians: identification of genes coding for rise of mortal disease.
Gene - 26 Nov 1998
Tomita-Mitchell A, Muniappan B P, Herrero-Jimenez P, Zarbl H, Thilly W G
Abstract excerpt
Some single-nucleotide polymorphisms (SNPs) increase the risk of mortal disease. Identifying these SNPs and the genes in which they reside is an important area in human genomics. Such qualitative observations are important in themselves. However, an accurate assessment of the numerical distribution and age-dependent decline of SNPs in the population would permit calculation of the rises represented by each SNP....
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