SCID mice containing muscle with human mitochondrial DNA mutations. An animal model for mitochondrial DNA defects.

Abstract excerpt

Defects of the mitochondrial genome are important causes of disease. Despite major advances in our investigation of patients, there is no effective therapy. Progress in this area is limited by the absence of any animal models in which we can evaluate treatment. To develop such a model we have inj...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Disease Models, Animal
• Share to DNA, Mitochondrial
• Share to Electron Transport Complex IV